HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine → 3,6-diethyl-N-(7-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine | HCID 13914592 | — |
| Reactant | (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol | HCID 58583341 | — |
| Product | 3,6-diethyl-N-(7-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)pyrazin-2-amine | HCID 22147465 | — |
Reaction Steps
Following the procedure for the preparation of (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting 7-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine and making non-critical variations provided the title compound as a oil: 1H NMR (400 MHz, CDCl3) δ 7.67, 7.08, 6.92, 6.81, 5.42, 4.54, 3.75, 2.84–2.77, 2.68, 2.56, 2.10, 1.88, 1.36–1.27; (MS/CI) calcd for C19H25N3O+H 312.4, found 312.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07041672B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-073cc1c1ac584d56ac0d60739e8454b8 |
| Source note | uspto-grants-2006_05 |