HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,5,6,7-Tetrahydro-1-benzofuran-4-amine → 5-Ethyl-4,5,6,7-tetrahydro-1-benzothiophen-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,5,6,7-Tetrahydro-1-benzofuran-4-amine | HCID 18525171 | — |
| Reactant | 5-ethyl-6,7-dihydro-1-benzothiophen-4(5H)-one | HCID 22147284 | — |
| Product | 5-Ethyl-4,5,6,7-tetrahydro-1-benzothiophen-4-amine | HCID 23593713 | — |
Reaction Steps
Following the procedure for the preparation of 4,5,6,7-tetrahydro-1-benzofuran-4-amine but substituting 5-ethyl-6,7-dihydro-1-benzothiophen-4(5H)-one and making non-critical variations provided the title compound as a oil: 1H NMR (400 MHz, CDCl3) δ) 7.10, 7.05, 6.99, 3.98, 3.65, 2.87–2.73, 2.06–1.90, 1.74–1.19, 1.05–0.97. (MS/CI) calcd for C10H15NS+H 182.3, found 181.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07041672B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-8e8777957b2846399c0c56e328406132 |
| Source note | uspto-grants-2006_05 |