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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1824132Generated: November 3, 2026

(1R,2S)-1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol → HCID 58583469, compound

https://huagongshe.com/reaction/1824132

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R,2S)-1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-olHCID 58583245—
ReactantHCID 58583320HCID 58583320—
ProductHCID 58583469HCID 58583469—

Reaction Steps

Following the procedure for the preparation of (1R,2S)-1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting 3,6-diethyl-N-[Trans-5-propyl-4,5,6,7-tetrahydro-1-benzothien-4-yl]pyrazin-2-amine and making non-critical variations provided the title compound as a oil: 1H NMR (300 MHz, CDCl3) δ 7.07, 6.82, 5.12, 4.41, 2.82, 2.56, 2.15–1.71, 1.68–1.40, 1.28, 0.92; HRMS (FAB) calcd for C19H26BrN3S+H 408.1109, found 408.1123.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07041672B2
Source datasetuspto-grants-2006_05
ORD IDord-04f8986ede5a4bac83965f3d874c4503
Source noteuspto-grants-2006_05