反应详情

Following the procedure for the preparation of (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting 6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine and making non-critical variations provided the title compound as a oil: 1H NMR (300 MHz, CDCl3) δ) 8.46, 7.60, 7.17, 5.37, 5.25, 3.11–2.95, 2.75–2.61, 1.94–1.81, 1.36–1.26; (MS/CI) calcd for C16H20N4+H 269.4, found 269.3.