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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1824180Generated: November 3, 2026

(1R,2S)-1-{[5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-yl]amino}-2,3-dihydro-1H-inden-2-ol → HCID 58583319, compound

https://huagongshe.com/reaction/1824180

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R,2S)-1-{[5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-yl]amino}-2,3-dihydro-1H-inden-2-olHCID 58583246—
ReactantHCID 58631223HCID 58631223—
ProductHCID 58583319HCID 58583319—

Reaction Steps

Following the procedure for the preparation of (1R,2S)-1-{[5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-yl]amino}-2,3-dihydro-1H-inden-2-ol but substituting (+/−)-5-bromo-3,6-diethyl-N-[trans-2-ethyl-2,3-dihydro-1H-inden-1-yl]pyrazin-2-amine and making non-critical variations provided the title compound as a light yellow semi-solid. IR (liq.) 3443, 2965, 2934, 2874, 1588, 1566, 1551, 1497, 1470, 1390, 1203, 1186, 1173, 1101, 747 cm−1; OAMS supporting ions at: ESI+ 440.0; MS (EI) m/z 439 (M+); Anal. Calcd for C25H27Cl2N3: C, 68.18; H, 6.18; N, 9.54. Found: C, 68.11; H, 6.17; N, 9.29.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07041672B2
Source datasetuspto-grants-2006_05
ORD IDord-33b7c560e66c4ca08a6b4b31464a9655
Source noteuspto-grants-2006_05