Alpha-Aminobutyric Acid → Methyl 2-aminobutanoate hydrochloride

HRID 1824232Notes

Reaction equation

[ClH:1].[NH2:2][CH:3]([CH:8]1C[CH2:9]1)[C:4]([O:6][CH3:7])=[O:5].NC(CC)C(O)=O>>[ClH:1].[NH2:2][CH:3]([CH2:8][CH3:9])[C:4]([O:6][CH3:7])=[O:5]

Participants

Reactant 2

HCID 6657Alpha-Aminobutyric Acid

HCID 46863945Methyl 2-amino-2-cyclopropylacetate hydrochloride

Product 1

HCID 13283515Methyl 2-aminobutanoate hydrochloride

Procedure

Following the procedure for the preparation of methyl amino(cyclopropyl)acetate hydrochloride but substituting alpha-aminobutyric acid and making non-critical variations provided the title compound as a solid: MS (ESI+) for C5H11NO2 m/z 235 (2M+H)+.

Sources & evidence

ORD record: ord-f6fd5058390743f890b1dc2f613678ed
Source dataset: uspto-grants-2006_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07041672B2

Reaction notes

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