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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1824252Generated: November 1, 2026

(1R,2S)-1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol → HCID 58583484, compound

https://huagongshe.com/reaction/1824252

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R,2S)-1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-olHCID 58583245—
ReactantHCID 58583262HCID 58583262—
ProductHCID 58583484HCID 58583484—

Reaction Steps

Following the procedure for the preparation of (1R,2S)-1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting (1R,2S)-1-[(6-cyclopropyl-3-ethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol and making non-critical variations provided the title compound as a solid: 1H NMR (CDCl3) δ 0.93–1.09, 1.28–1.39, 2.35–2.43, 2.60–2.67, 2.99–3.05, 3.22–3.29, 4.70, 5.04, 5.44–5.49, 7.23–7.32; MS (ESI+) for C18H20BrN3O m/z 374 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07041672B2
Source datasetuspto-grants-2006_05
ORD IDord-69c0e5e35c5740cfa6fa9740e0c26397
Source noteuspto-grants-2006_05