5-(2,4-dichlorophenyl)-N-[(1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl]-3,6-diethylpyrazin-2-amine → HCID 58583402, compound

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Reaction Steps

Following the procedure for the preparation of 5-(2,4-dichlorophenyl)-N-[(1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl]-3,6-diethylpyrazin-2-amine but substituting (1R,2S)-1-({6-cyclopropyl-5-[6-(dimethylamino)-4-methylpyridin-3-yl]-3-ethylpyrazin-2-yl}amino)-2,3-dihydro-1H-inden-2-ol and making non-critical variations provided the title compound as a solid: 1H NMR (CDCl3) δ 0.81–1.19, 1.28–1.33, 2.67–2.73, 3.11–3.14, 3.42–3.51, 3.65–3.73, 4.32–4.35, 5.40–5.42, 5.72–5.75, 6.497.22–7.39, 8.19; MS (ESI+) for C28H35N5O m/z 458 (M+H)+.

Provenance & Evidence