5-(2,4-dichlorophenyl)-N-[(1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl]-3,6-diethylpyrazin-2-amine → HCID 58583478, compound

Participants

Reaction Steps

Following the procedure for the preparation of 5-(2,4-dichlorophenyl)-N-[(1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl]-3,6-diethylpyrazin-2-amine but substituting (1R,2S)-1-{[3-cyclopropyl-5-(2,4-dichlorophenyl)-6-ethylpyrazin-2-yl]amino}-2,3-dihydro-1H-inden-2-ol and making non-critical variations provided the title compound as a solid: 1H NMR (CDCl3) δ 0.87–1.21, 1.58, 1.80–1.85, 2.51, 3.15–3.17, 3.46–3.56, 3.66–3.76, 4.40–4.45, 5.88, 6.04, 7.21–7.34, 7.47–7.50; MS (ESI+) for C26H27Cl2N3O m/z 469 (M+H)+.

Provenance & Evidence