5-(2,4-dichlorophenyl)-N-[(1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl]-3,6-diethylpyrazin-2-amine → HCID 58583275, compound

Participants

Reaction Steps

Following the procedure for the preparation of 5-(2,4-dichlorophenyl)-N-[(1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl]-3,6-diethylpyrazin-2-amine but substituting (1R,2S)-1-{[5-(2,4-dichlorophenyl)-6-ethyl-3-methylpyrazin-2-yl]amino}-2,3-dihydro-1H-inden-2-ol and making non-critical variations provided the title compound as a solid: 1H NMR (CDCl3) δ 0.76–0.82, 1.02–1.34, 1.56–1.58, 2.24, 2.62, 3.38–3.55, 3.90–3.95, 5.22, 5.50–5.54, 6.14–6.16, 6.70–6.72, 7.04–7.62; MS (ESI+) for C24H25Cl2N3O m/z 443 (M+H)+.

Provenance & Evidence