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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1824380Generated: October 27, 2026

2-Chloro-1-fluoro-4-nitrobenzene → 2-(2-Chloro-4-nitro-phenylsulfanyl)-5-trifluoromethyl-benzothiazole

https://huagongshe.com/reaction/1824380

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-1-fluoro-4-nitrobenzeneHCID 67688—
Reactant5-(trifluoromethyl)-1,3-benzothiazole-2-thiolHCID 178419087—
Product2-(2-Chloro-4-nitro-phenylsulfanyl)-5-trifluoromethyl-benzothiazoleHCID 22148837—

Reaction Steps

2-(2-Chloro-4-nitro-phenylsulfanyl)-5-trifluoromethyl-benzothiazole (252) was prepared (92%) from 2-chloro-1-fluoro-4-nitrobenzene, obtained from Aldrich, and 5-trifluoromethyl-benzothiazol-2-thiol (239) in a similar manner as described in example 251.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07041691B1
Source datasetuspto-grants-2006_05
ORD IDord-cfafcbf582fc4b16b74e425fdb03ca33
Source noteuspto-grants-2006_05