HCID 178469002, compound → HCID 178469003, compound

Participants

Reaction Steps

970 mg of trans-1,4-diaminocyclohexane are heated to its melting point (70° C.), 269 mg of the product obtained in stage 1 above are added and the medium is then heated at 140–145° C. for 4 hours. The medium is allowed to return to room temperature and it is taken up in 50 ml of a CH2Cl2-methanol: 80-20 mixture. The medium is washed twice with 20 ml of H2O and once with 20 ml of sodium chloride as a saturated aqueous solution. The medium is dried over Na2SO4 and evaporated to dryness.

Provenance & Evidence