Ethyl 3-aminobenzoate → HCID 178468894, compound

HRID 1824459Notes

Reaction equation

HRID 1824459 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[C:4](Cl)[N:3]=1.[NH2:12][C:13]1[CH:14]=[C:15]([CH:21]=[CH:22][CH:23]=1)[C:16]([O:18][CH2:19][CH3:20])=[O:17]>C(O)CCC>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][NH:8]2)=[C:4]([NH:12][C:13]2[CH:14]=[C:15]([CH:21]=[CH:22][CH:23]=2)[C:16]([O:18][CH2:19][CH3:20])=[O:17])[N:3]=1

Participants

4

Reactant 2

HCID 11400Ethyl 3-aminobenzoateHCID 53244122,6-Dichloropurine

Product 1

HCID 178468894HCID 178468894, compoundYield 86.6%

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

The procedure is carried out as in Example 1, starting with 189 mg of 2,6-dichloropurine, 5 ml of butanol and 206 mg of ethyl 3-aminobenzoate. 275 mg of the expected product are thus obtained.

Sources & evidence

ORD record
ord-b82743e3a24f473cb6b74485d0ad984f
Source dataset
uspto-grants-2006_05
Patent number
US07041824B2

Reaction notes

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