HCID 178468894, compound → HCID 178468897, compound

HRID 1824460Notes

Reaction equation

HRID 1824460 reaction equation
[NH2:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([NH2:8])[CH2:4][CH2:3]1.Cl[C:10]1[N:18]=[C:17]2[C:13]([N:14]=[CH:15][NH:16]2)=[C:12]([NH:19][C:20]2[CH:21]=[C:22]([CH:28]=[CH:29][CH:30]=2)[C:23]([O:25][CH2:26][CH3:27])=[O:24])[N:11]=1>>[NH2:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([NH:8][C:10]2[N:18]=[C:17]3[C:13]([N:14]=[CH:15][NH:16]3)=[C:12]([NH:19][C:20]3[CH:21]=[C:22]([CH:28]=[CH:29][CH:30]=3)[C:23]([O:25][CH2:26][CH3:27])=[O:24])[N:11]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 178468894HCID 178468894, compoundHCID 178511674HCID 178511674, compound

Product 1

HCID 178468897HCID 178468897, compoundYield 16.3%

Procedure

570 mg of trans 1,4-diaminocyclohexane are heated to its melting point (70° C.) and 158 mg of the product obtained in stage 1 above are added. 32 mg of the expected product are thus obtained.

Workup

  1. additionabove are added

Sources & evidence

ORD record
ord-221a41ad13bf49679ba09758d2e97792
Source dataset
uspto-grants-2006_05
Patent number
US07041824B2

Reaction notes

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