Butyl 4-aminobenzoate → HCID 178450729, compound

HRID 1824464Notes

Reaction equation

HRID 1824464 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[C:4](Cl)[N:3]=1.[NH2:12][C:13]1[CH:25]=[CH:24][C:16]([C:17]([O:19][CH2:20][CH2:21][CH2:22][CH3:23])=[O:18])=[CH:15][CH:14]=1>C(O)CCC>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][NH:8]2)=[C:4]([NH:12][C:13]2[CH:14]=[CH:15][C:16]([C:17]([O:19][CH2:20][CH2:21][CH2:22][CH3:23])=[O:18])=[CH:24][CH:25]=2)[N:3]=1

Participants

4

Reactant 2

HCID 2482Butyl 4-aminobenzoateHCID 53244122,6-Dichloropurine

Product 1

HCID 178450729HCID 178450729, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

The procedure is carried out as in Example 1, starting with 472.5 mg of 2,6-dichloropurine, 5 ml of butanol and 602.9 mg of butyl 4-aminobenzoate. 864.5 mg of the expected product are thus obtained.

Sources & evidence

ORD record
ord-1c3ce4e1d7f34623b80fbdf1193aca60
Source dataset
uspto-grants-2006_05
Patent number
US07041824B2

Reaction notes

Loading…