4-Amino-N-phenylbenzamide → HCID 178521922, compound

HRID 1824468Notes

Reaction equation

HRID 1824468 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[C:4](Cl)[N:3]=1.[NH2:12][C:13]1[CH:27]=[CH:26][C:16]([C:17]([NH:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[O:18])=[CH:15][CH:14]=1>C(O)CCC>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][NH:8]2)=[C:4]([NH:12][C:13]2[CH:27]=[CH:26][C:16]([C:17]([NH:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[O:18])=[CH:15][CH:14]=2)[N:3]=1

Participants

4

Reactant 2

HCID 699104-Amino-N-phenylbenzamideHCID 53244122,6-Dichloropurine

Product 1

HCID 178521922HCID 178521922, compoundYield 95.7%

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

The procedure is carried out as in Example 1, starting with 195 mg of 2,6-dichloropurine, 5 ml of butanol and 272 mg of 4-amino-N-phenylbenzamide. 360 mg of the expected product are thus obtained.

Sources & evidence

ORD record
ord-a5855936c088417fb36169e3ccc2ccdd
Source dataset
uspto-grants-2006_05
Patent number
US07041824B2

Reaction notes

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