HCID 178511674, compound → HCID 178511672, compound

HRID 1824469Notes

Reaction equation

HRID 1824469 reaction equation
[NH2:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([NH2:8])[CH2:4][CH2:3]1.Cl[C:10]1[N:18]=[C:17]2[C:13]([N:14]=[CH:15][NH:16]2)=[C:12]([NH:19][C:20]2[CH:34]=[CH:33][C:23]([C:24]([NH:26][C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)=[O:25])=[CH:22][CH:21]=2)[N:11]=1>>[NH2:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([NH:8][C:10]2[N:18]=[C:17]3[C:13]([N:14]=[CH:15][NH:16]3)=[C:12]([NH:19][C:20]3[CH:34]=[CH:33][C:23]([C:24]([NH:26][C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=4)=[O:25])=[CH:22][CH:21]=3)[N:11]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 178511674HCID 178511674, compoundHCID 178521922HCID 178521922, compound

Product 1

HCID 178511672HCID 178511672, compoundYield 9.6%

Procedure

937 mg of trans-1,4-diaminocyclohexane are heated to its melting point (70° C.) and 300 mg of the product obtained in stage 1 above are added. 35 mg of the expected product are thus obtained.

Workup

  1. additionabove are added

Sources & evidence

ORD record
ord-691f93809e324aee9dc8098dea449c6d
Source dataset
uspto-grants-2006_05
Patent number
US07041824B2

Reaction notes

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