4-Aminobenzamide → HCID 178513663, compound

HRID 1824474Notes

Reaction equation

HRID 1824474 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[C:4](Cl)[N:3]=1.[NH2:12][C:13]1[CH:21]=[CH:20][C:16]([C:17]([NH2:19])=[O:18])=[CH:15][CH:14]=1>C(O)CCC>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][NH:8]2)=[C:4]([NH:12][C:13]2[CH:21]=[CH:20][C:16]([C:17]([NH2:19])=[O:18])=[CH:15][CH:14]=2)[N:3]=1

Participants

4

Reactant 2

HCID 760794-AminobenzamideHCID 53244122,6-Dichloropurine

Product 1

HCID 178513663HCID 178513663, compoundYield 114%

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

The procedure is carried out as in Example 1, starting with 189 mg of 2,6-dichloropurine, 5 ml of butanol and 150 mg of 4-aminobenzamide. 329 mg of the expected product are thus obtained.

Sources & evidence

ORD record
ord-c766d6cbfd624c2180526e611ad5e475
Source dataset
uspto-grants-2006_05
Patent number
US07041824B2

Reaction notes

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