HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[4-[4-Hydroxybut-1-ynyl]phenyl]-7-methylimidazo[1,2-a]pyridine → 2-[4-[4-Hydroxybutyl]phenyl]-7-methylimidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[4-[4-Hydroxybut-1-ynyl]phenyl]-7-methylimidazo[1,2-a]pyridine | HCID 22015594 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-[4-[4-Hydroxybutyl]phenyl]-7-methylimidazo[1,2-a]pyridine | HCID 22015655 | 92.6% |
Reaction Steps
The product of Step B, Example 33 (0.3 g) in ethanol (15 mL) was hydrogenated over 5% palladium on barium sulfate (0.06 g) for 4.5 hours. The reaction mixture was filtered and evaporated to afford the title compound (0.282 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07041827B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-8311ef7cf0ee4daa9a5d1170dc0d2a14 |
| Source note | uspto-grants-2006_05 |