HCID 58632371, compound → HCID 22141991, compound

HRID 1824662Notes

Reaction equation

HRID 1824662 reaction equation
[C:1]([O:4][C@H:5]([C:9]1[S:10][CH:11]=[CH:12][CH:13]=1)[CH2:6][C:7]#[N:8])(=[O:3])[CH3:2]>C(Cl)(Cl)Cl>[C:1]([O:4][CH:5]([C:9]1[S:10][CH:11]=[CH:12][CH:13]=1)[CH2:6][C:7]#[N:8])(=[O:3])[CH3:2]

Participants

3

Reactant 1

HCID 58632371HCID 58632371, compound

Product 1

HCID 22141991HCID 22141991, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Yield of (S)-3-acetyloxy-3-(2-thienyl) propanenitrile (S-2) 43%, ee >99%, [α]30D=−82.1 (c 1, CHCl3).

Sources & evidence

ORD record
ord-564832f585b842adacdf2e94241affa4
Source dataset
uspto-grants-2006_05
Patent number
US07045341B2

Reaction notes

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