HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-nitro-4-(3-(trifluoromethyl)phenoxy)benzene → 4-[3-(trifluoromethyl)phenoxy]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-nitro-4-(3-(trifluoromethyl)phenoxy)benzene | HCID 243309 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-[3-(trifluoromethyl)phenoxy]aniline | HCID 2760750 | 100.1% |
Reaction Steps
To 1-Nitro-4-[3-(trifluoromethyl)phenoxy]benzene (19 g) in ethyl acetate (250 mL) was added 5% palladium on charcoal (1.5 g). The mixture was stirred under hydrogen gas for about 36 h, and then filtered through Celite. The filtrate was concentrated to yield a red oil (17 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07045512B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-13ec510c415549bfac230dff980eced0 |
| Source note | uspto-grants-2006_05 |