Boron → HCID 22144521, compound

HRID 1824803Notes

Reaction equation

HRID 1824803 reaction equation
C[O:2][C:3]1[CH:20]=[CH:19][C:6]2[N:7]=[C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[C:12]([O:16]C)[C:11]=3[CH3:18])[S:9][C:5]=2[CH:4]=1.[B]>>[OH:2][C:3]1[CH:20]=[CH:19][C:6]2[N:7]=[C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[C:12]([OH:16])[C:11]=3[CH3:18])[S:9][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 5462311BoronHCID 22144506HCID 22144506, compound

Product 1

HCID 22144521HCID 22144521, compoundYield 90.2%

Procedure

6-Methoxy-2-(2-methyl-3-methoxy-phenyl)-benzothiazole (64 mg, 0.224 mmol) was treated with boron tribroride under standard condition to give 6-hydroxy-2-(2-methyl-3-hydroxy-phenyl)-benzothiazole (52 mg, 90% yield) as a yellow solid. Mass spec: MH+=258.

Sources & evidence

ORD record
ord-0d391e0824d1401a8637d0f3af9b008f
Source dataset
uspto-grants-2006_05
Patent number
US07045539B2

Reaction notes

Loading…