Boron tribromide → HCID 22144544, compound

HRID 1824806Notes

Reaction equation

HRID 1824806 reaction equation
[C:1]([C:3]1[C:8]2[N:9]=[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([O:18]C)[C:13]=3[CH2:20][CH3:21])[S:11][C:7]=2[CH:6]=[C:5]([O:22]C)[CH:4]=1)#[N:2].B(Br)(Br)Br>>[C:1]([C:3]1[C:8]2[N:9]=[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([OH:18])[C:13]=3[CH2:20][CH3:21])[S:11][C:7]=2[CH:6]=[C:5]([OH:22])[CH:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 22144499HCID 22144499, compound

Product 1

HCID 22144544HCID 22144544, compoundYield 33%

Procedure

4-Cyano-6-methoxy-2-(2-ethyl-3-methoxy-phenyl)-benzothiazole (0.1 g, 0.31 mmol) was treated with boron tribromide under standard condition to give the title compound (30 mg, 33% yield) as a yellow solid. Mass spec:MH+=297.

Sources & evidence

ORD record
ord-05757deda1794bae8d14e5a1e50f1a1b
Source dataset
uspto-grants-2006_05
Patent number
US07045539B2

Reaction notes

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