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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1824877생성일: 2026년 10월 25일

4-(Trifluoromethyl)benzenesulfonamide → N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-4-trifluoromethyl-benzenesulfonamide

https://huagongshe.com/reaction/1824877

반응식

참여 물질

역할이름HCID투입량
반응물4-(Trifluoromethyl)benzenesulfonamideHCID 70018—
반응물3-[4-(Z)-(1,2-diphenylbut-1-enyl)phenyl]-acrylic acidHCID 3036152—
생성물N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-4-trifluoromethyl-benzenesulfonamideHCID 69780578—

반응 단계

Prepared by coupling 1a and 4-(trifluoromethyl)-benzenesulfonamide (Synlett, 1997, 375) in accordance with Procedure 1, Method B described hereinabove. Yield (18%); 1H NMR (d6-DMSO) δ 12.46 (br s, 1H), 8.11 (d, J=8.5 Hz, 2H), 7.99 (d, J=8.5 Hz, 2H), 7.40–7.07 (m, 13H), 6.84 (d, J=8.1 Hz, 2H), 6.40 (d, J=15.7 Hz, 1H), 2.35 (q, J=7.3 Hz, 2H), 0.81 (t, J=7.3 Hz, 3H); APcI m/z: 562 (M+H+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07045540B2
출처 데이터셋uspto-grants-2006_05
ORD IDord-1845eabeb0334af383295056a1f54fd4
출처 메모uspto-grants-2006_05