m-Toluenesulphonamide → N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-3-methyl-benzenesulfonamide

Participants

Role	Name	HCID	Charge
Reactant	m-Toluenesulphonamide	HCID 74697	—
Reactant	3-[4-(Z)-(1,2-diphenylbut-1-enyl)phenyl]-acrylic acid	HCID 3036152	—
Product	N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-3-methyl-benzenesulfonamide	HCID 69781095	—

Reaction Steps

Prepared by coupling 1a and m-toluenesulfonamide (Synlett, 1997, 375) in accordance with Procedure 1, Method B described hereinabove. Yield (24%); 1H NMR (CDCl3) δ 7.86 (m, 2H), 7.50 (d, J=15.7 Hz, 1H), 7.42–7.07 (m, 14H), 6.86 (d, J=8.4 Hz, 2H), 6.27 (d, J=15.7 Hz, 1H), 2.47 (q, J=7.3 Hz, 2H), 2.41 (s, 3H), 0.93 (t, J=7.3 Hz, 3H); APcI m/z: 508 (M+H+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07045540B2
Source dataset	uspto-grants-2006_05
ORD ID	ord-409817def12047b9a93c8c7290e4af22
Source note	uspto-grants-2006_05