HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosuccinimide → N-tert-butoxycarbonyl 1-(2-chloro-5-fluorobenzofur-7-yl)-2-aminopropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | N-tert-butoxycarbonyl 1-(5-fluorobenzofur-7-yl)-2-aminopropane | HCID 22144858 | — |
| Product | N-tert-butoxycarbonyl 1-(2-chloro-5-fluorobenzofur-7-yl)-2-aminopropane | HCID 22144768 | 43% |
Reaction Steps
Beginning with 0.29 gm (1.0 mMol) N-tert-butoxycarbonyl 1-(5-fluorobenzofur-7-yl)-2-aminopropane and 0.16 gm (1.20 mMol) N-chlorosuccinimide, 0.14 gm (43%) of the desired compound were prepared essentially as described in EXAMPLE 16.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07045545B1 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-ff9fac9f7abb41dbac1565d1767841ef |
| Source note | uspto-grants-2006_05 |