Oxalic Acid → HCID 22144743, compound

HRID 1824964Notes

Reaction equation

HRID 1824964 reaction equation
FC1C=C(Br)C2OC=CC=2C=1.[F:12][C:13]1[CH:14]=[C:15]([CH:22]([CH2:25][CH3:26])[CH2:23][NH2:24])[C:16]2[O:20][CH:19]=[CH:18][C:17]=2[CH:21]=1.[C:27]([OH:32])(=[O:31])[C:28]([OH:30])=[O:29]>>[C:27]([OH:32])(=[O:31])[C:28]([OH:30])=[O:29].[F:12][C:13]1[CH:14]=[C:15]([CH:22]([CH2:25][CH3:26])[CH2:23][NH2:24])[C:16]2[O:20][CH:19]=[CH:18][C:17]=2[CH:21]=1

Participants

4

Reactant 3

HCID 971Oxalic AcidHCID 22144707HCID 22144707, compoundHCID 221448167-Bromo-5-fluoro-1-benzofuran

Product 1

HCID 22144743HCID 22144743, compound

Procedure

Beginning with 5-fluoro-7-bromobenzofuran, 2-(5-fluorobenzofur-7-yl)-1-aminobutane was prepared essentially as described in EXAMPLE 39. This amine was treated with oxalic acid to provide the title compound.

Workup

  1. customwas prepared essentially

Sources & evidence

ORD record
ord-32fa1bc169974a63a3724ed2177aff48
Source dataset
uspto-grants-2006_05
Patent number
US07045545B1

Reaction notes

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