Oxalic Acid → HCID 22144747, compound

HRID 1824965Notes

Reaction equation

HRID 1824965 reaction equation
FC1C=C(Br)C2OC=CC=2C=1.[F:12][C:13]1[CH:14]=[C:15]([CH:22]([CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:23][NH2:24])[C:16]2[O:20][CH:19]=[CH:18][C:17]=2[CH:21]=1.[C:32]([OH:37])(=[O:36])[C:33]([OH:35])=[O:34]>>[C:32]([OH:37])(=[O:36])[C:33]([OH:35])=[O:34].[F:12][C:13]1[CH:14]=[C:15]([CH:22]([CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:23][NH2:24])[C:16]2[O:20][CH:19]=[CH:18][C:17]=2[CH:21]=1

Participants

4

Reactant 3

HCID 971Oxalic AcidHCID 22144748HCID 22144748, compoundHCID 221448167-Bromo-5-fluoro-1-benzofuran

Product 1

HCID 22144747HCID 22144747, compound

Procedure

Beginning with 5-fluoro-7-bromobenzofuran, 2-(5-fluorobenzofur-7-yl)-3-phenylprop-1-ylamine was prepared essentially as described in EXAMPLE 39. This amine was treated with oxalic acid to provide the title compound.

Workup

  1. customwas prepared essentially

Sources & evidence

ORD record
ord-191ef6d5d6ce4769b80f4fb6756dd8c4
Source dataset
uspto-grants-2006_05
Patent number
US07045545B1

Reaction notes

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