HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-Bromo-o-fluorotoluene → Ethyl 1-(2-fluorobenzyl)-5-nitro-1H-indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha-Bromo-o-fluorotoluene | HCID 67968 | — |
| Reactant | Ethyl 5-nitro-1H-indole-2-carboxylate | HCID 280312 | — |
| Product | Ethyl 1-(2-fluorobenzyl)-5-nitro-1H-indole-2-carboxylate | HCID 12068605 | — |
Reaction Steps
The preparation is carried out as described for Example I using 940 mg (4.00 mmol) of ethyl 5-nitro-1H-indole-2-carboxylate and 780 mg (4.15 mmol) of 2-fluorobenzyl bromide, reaction time 6 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07045544B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-218ae6691ca444d99ebdec518de7f21c |
| Source note | uspto-grants-2006_05 |