Trifluoroacetic acid → HCID 23573494, compound

Participants

Reaction Steps

A solution of TFA (5 mL) and (1R,2S)-(2,3-dihydroxy-1-naphthalen-2-yl-propyl)-carbamic acid tert-butyl ester (1.72 g) in methylene chloride (15 mL) was stirred for 2 h. After concentration, the residue was neutralized with 10 N NaOH and extracted with methylene chloride. The combined organic layer was washed with brine, dried over Na2SO4, and concentrated in vacuo to give the title compound as a solid (1.1 g).

Provenance & Evidence