HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylbut-1-yne → 6-Methoxy-2-(1-methylethyl)benzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylbut-1-yne | HCID 69019 | — |
| Reactant | 2-Iodo-5-methoxyphenol | HCID 11414015 | — |
| Product | 6-Methoxy-2-(1-methylethyl)benzofuran | HCID 10797752 | 38% |
Reaction Steps
Example 15(a) was prepared from 2-iodo-5-methoxyphenol (896 mg, 3.6 mmole) and 3-methyl-1-butyne in a manner as previously described for example 12a to give 265 mg (38%) of an amber oil. 1H NMR (CDCl3) δ 7.33 (1H, d, J=8.6 Hz), 6.97 (1H, d, J=2.2 Hz), 6.80 (1H, dd, J=2.2, 8.6 Hz), 6.26 (1H, s), 3.83 (3H, s), 3.07–3.01 (1H, m), 1.31 (6H, d, J=7.1 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07045528B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-21edc71dff604a628dc353f1430e87ac |
| Source note | uspto-grants-2006_05 |