Thionyl Chloride → HCID 11206726, compound

HRID 1825296Notes

Reaction equation

HRID 1825296 reaction equation
Cl.Cl[CH2:3][C:4]1[CH:5]=[N:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[CH:9][CH:8]=2.N1C2C(=CC=CC=2)C=[C:16]([CH2:24][OH:25])C=1.[S:26](Cl)(Cl)=O>C1C=CC=CC=1>[C:24]([S:26][CH2:3][C:4]1[CH:5]=[N:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[CH:9][CH:8]=2)(=[O:25])[CH3:16]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 69584718HCID 69584718, compound

Product 1

HCID 11206726HCID 11206726, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

3-Chloromethylquinoline hydrochloride—3-Quinolylmethanol (9.85 g) was taken up in dry benzene (200 ml) and stirred followed by the addition of thionyl chloride (14.69 ml). An immediate yellow precipitate was obtained. Stirring was maintained at rt for 2 h. A light yellow solid was filtered off and dried to give the subtitle compound (13 g).

Workup

  1. customAn immediate yellow precipitate was obtained
  2. stirringStirring
  3. filtrationA light yellow solid was filtered off
  4. customdried

Sources & evidence

ORD record
ord-c7eb1712369c450a86a35e6e6cd5555d
Source dataset
uspto-grants-2006_05
Patent number
US07045626B2

Reaction notes

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