Ethanol → N-{4-[2-Amino-3,5-dicyano-6-(phenylsulphanyl)-4-pyridinyl]phenyl}acetamide

Participants

Reaction Steps

318 g (1.5 mol) of N-[4-(2,2-dicyanovinyl)phenyl]acetamide, 99 g (1.5 mol) of malonitrile and 166 g (1.5 mol) of thiophenol are initially introduced in 2 000 ml of ethanol, and 6.7 ml of triethylamine are then added. The mixture is stirred under reflux for 2 hours, in connection with which crystallization takes place. After the mixture has cooled down to room temperature, the product is filtered off with suction and dried in vacuo.

Provenance & Evidence