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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1825562Generated: October 26, 2026

2-Fluoro-4-(trifluoromethyl)benzoyl chloride → {4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}{2-[(5-nitro(2-pyridyl))amino]ethyl}amine

https://huagongshe.com/reaction/1825562

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-(trifluoromethyl)benzoyl chlorideHCID 145580—
ReactantChir-98023HCID 9847557—
Product{4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}{2-[(5-nitro(2-pyridyl))amino]ethyl}amineHCID 22142905—

Reaction Steps

{4-[2-fluoro-4-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}{2-[(5-nitro(2-pyridyl))amino]ethyl}amine was prepared from 2-fluoro-4-(trifluoromethyl)benzoyl chloride using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07045519B2
Source datasetuspto-grants-2006_05
ORD IDord-3b510979198a4ff4b847db3afa915379
Source noteuspto-grants-2006_05