HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethylbenzoyl chloride → 6-[(2-{[4-(4-Ethylphenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino}ethyl)amino]-pyridine-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethylbenzoyl chloride | HCID 85368 | — |
| Reactant | 6-Chloro-3-pyridinecarbonitrile | HCID 5152094 | — |
| Reactant | Chir-98023 | HCID 9847557 | — |
| Product | 6-[(2-{[4-(4-Ethylphenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino}ethyl)amino]-pyridine-3-carbonitrile | HCID 22143053 | — |
Reaction Steps
6-[(2-{[4-(4-ethylphenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile was prepared from 4-ethylbenzoyl chloride and 2-chloro-5-(cyano)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl})amino]ethyl}amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07045519B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-9367ccabf8c24f84968c520a8dc862fb |
| Source note | uspto-grants-2006_05 |