HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(1H-Indol-5-ylmethyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | (1H-indol-5-yl)methanamine | HCID 54791 | — |
| Product | N-(1H-Indol-5-ylmethyl)acetamide | HCID 22139217 | 89% |
Reaction Steps
5-Aminomethylindole (5.3 g, 0.036 mol) was mixed with acetic anhydride (13 ml) and kept at room temperature for 3 h. The solvent was removed under reduced pressure and the residue was stirred with toluene. The precipitated solid was collected by filtration to yield 6.1 g (89%) of 5-acetaminomethylindole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07049312B1 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-04aecfa4375447b197935186b319bdca |
| Source note | uspto-grants-2006_05 |