HCID 58633713, compound → HCID 23574642, compound

HRID 1825758Notes

Reaction equation

C(OC(=O)N(CCCC1C=CC([Cl:38])=CC=1)[C@@H]1CCC[C@H]1NC(NC1C=C(OC)C(OC)=C(OC)C=1)=O)(C)(C)C.C(OC(=O)[N:46]([CH2:65][CH2:66][C:67]1[CH:72]=[CH:71][C:70]([Cl:73])=[CH:69][CH:68]=1)[C@@H:47]1[CH2:51][CH2:50][CH2:49][C@H:48]1[NH:52][C:53](=[O:64])[C:54]1[CH:59]=[CH:58][C:57]([S:60]([CH3:63])(=[O:62])=[O:61])=[CH:56][CH:55]=1)(C)(C)C>>[ClH:38].[Cl:73][C:70]1[CH:71]=[CH:72][C:67]([CH2:66][CH2:65][NH:46][C@@H:47]2[CH2:51][CH2:50][CH2:49][C@H:48]2[NH:52][C:53](=[O:64])[C:54]2[CH:55]=[CH:56][C:57]([S:60]([CH3:63])(=[O:61])=[O:62])=[CH:58][CH:59]=2)=[CH:68][CH:69]=1

Participants

Reactant 2

HCID 58633713HCID 58633713, compound

HCID 69584524HCID 69584524, compound

Product 1

HCID 23574642HCID 23574642, compound

Procedure

Using procedures similar to those described in Example 3, except replacing the (±)-trans-[3-(4-chlorophenyl)propyl]-{2-[3-(3,4,5-trimethoxyphenyl)ureido]-cyclopentyl}carbamic acid tert-butyl ester used therein with (±)-trans-[2-(4-chlorophenyl)ethyl]-[2-(4-methanesulfonylbenzoylamino)cyclopentyl]carbamic acid tert-butyl ester, the title compound was prepared; MS m/z 421 (M+1)+.

Sources & evidence

ORD record: ord-da3caf67d24b432e9d62cf66211a9bd6
Source dataset: uspto-grants-2006_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07049317B2

Reaction notes

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