p-(Methylsulphonyl)benzoic acid → HCID 23574644, compound

HRID 1825759Notes

Reaction equation

HRID 1825759 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][N:10]([CH3:17])[C@@H:11]2[CH2:15][CH2:14][CH2:13][C@H:12]2[NH2:16])=[CH:4][CH:3]=1.[CH3:18][S:19]([C:22]1[CH:30]=[CH:29][C:25]([C:26](O)=[O:27])=[CH:24][CH:23]=1)(=[O:21])=[O:20]>>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][N:10]([CH3:17])[C@@H:11]2[CH2:15][CH2:14][CH2:13][C@H:12]2[NH:16][C:26](=[O:27])[C:25]2[CH:24]=[CH:23][C:22]([S:19]([CH3:18])(=[O:21])=[O:20])=[CH:30][CH:29]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 77670p-(Methylsulphonyl)benzoic acidHCID 11817623HCID 11817623, compound

Product 1

HCID 23574644HCID 23574644, compound

Procedure

Using General Procedure D, as described in Example 2, Step A, the title compound was prepared from (±)-trans-N-[2-(4-chlorophenyl)ethyl]-N-methylcyclopentane-1,2-diamine and 4-methylsulfonylbenzoic acid MS m/z 435 (M+1)+.

Sources & evidence

ORD record
ord-0ec1c45d6675445eab5ce0de42b81d2f
Source dataset
uspto-grants-2006_05
Patent number
US07049317B2

Reaction notes

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