HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Water → 5-Bromo-6-methoxy-2-methylthioquinoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Water | HCID 962 | — |
| Edukt | 5-Bromo-2-methanesulfonyl-6-methoxy-quinoline | HCID 22139732 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 5-Bromo-6-methoxy-2-methylthioquinoline | HCID 22139696 | — |
Reaktionsschritte
The 5-bromo-2-methanesulfonyl-6-methoxy-quinoline was dissolved in 20 mL DMF and treated with 3 eq NaSCH3. After stirring 1 hour at room temperature the mixture was poured into water and extracted with ether. The crystalline product, 5-bromo-6-methoxy-2-methylsulfanyl-quinoline, was isolated in quantitative yield.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07049325B2 |
| Quelldatensatz | uspto-grants-2006_05 |
| ORD ID | ord-0b7c09262ddf44c49e91fbe659baecaf |
| Quellennotiz | uspto-grants-2006_05 |