Potassium Cation → 4-(1-Bromo-1-phenyl-methylene)-piperidine-1-carboxylic Acid tert-butyl Ester

HRID 182609Notes

Reaction equation

HRID 182609 reaction equation
[Br:27][Br:28].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[CH:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH3:36][OH:37].[Cl:31][CH:32]([Cl:33])[Cl:34].[K+:21].[K+:22].[Na+:30].[O-:23][C:24]([O-:25])=[O:26].[OH-:29].[OH2:35]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[C:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[Br:27])[CH2:12][CH2:13]1

Participants

10

Reactant 9

HCID 813Potassium Cation2×HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6212ChloroformHCID 19660Carbonate IonHCID 24408BromineHCID 40418559Tert-butyl 4-benzylidenepiperidine-1-carboxylate

Product 1

HCID 590345854-(1-Bromo-1-phenyl-methylene)-piperidine-1-carboxylic Acid tert-butyl Ester

Sources & evidence

ORD record
ord-f85351c2bf5e49fbbfeac7bcbe5be2e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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