HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,3-dimethyl-1H-indole-2-carbaldehyde → 7-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,3-dimethyl-1H-indole-2-carbaldehyde | HCID 2771468 | — |
| Edukt | 7-Fluoro-1-methylindole-3-carboxaldehyde | HCID 22139037 | — |
| Edukt | Methyl 2-((5-bromopyridin-2-yl)amino)acetate | HCID 22139049 | — |
| Produkt | 7-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole | HCID 22139066 | 72% |
Reaktionsschritte
According to the procedure of Preparation 11 (c), except substituting 7-fluoro-1-methyl-1H-indole-3-carboxaldehyde (0.23, 1.3 mmole) for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (0.18 g, 72%) was prepared as a viscous oil: MS (ES) m/e 193 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07741339B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-a4dc774b997848f2b92cd6333ab7d5ff |
| Quellennotiz | uspto-grants-2010_06 |