HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → 4-(5-Undecyl-pyrimidin-2-yl)phenyl 3-ethyl-1-cyclopentene-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 3-Ethyl-1-cyclopentene-1-carboxylic acid | HCID 22134221 | — |
| Reactant | 4-(5-Undecylpyrimidin-2-yl)phenol | HCID 135619682 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(5-Undecyl-pyrimidin-2-yl)phenyl 3-ethyl-1-cyclopentene-1-carboxylate | HCID 15514978 | — |
Reaction Steps
4.9 g of 4-(5-undecyl-pyrimidin-2-yl)phenol, 1.5 g of 3-ethyl-1-cyclopentene-1-carboxylic acid and 2.1 g of dicyclohexylcarbodiimide are stirred for 24 h in 50 ml of dichloromethane at room temperature. Filtration, removal of the dichloromethane by distillation, purification by chromatography (silica gel; dichloromethane/heptane) and recrystallization from acetonitrile affords the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07052742B1 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-4322494066cc4a929d8fbfd18ddf3161 |
| Source note | uspto-grants-2006_05 |