(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → (3S,4S,5R)-1,3,4,5,6-pentahydroxyhexan-2-one

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Reaction Steps

U.S. Pat. No. 6,057,135 discloses a process for manufacturing D-tagatose, wherein a lactose permeate is hydrolysed to obtain a lactose hydrolysate comprising D-galactose and glucose. The hydrolysate is fermented to convert the glucose to ethanol which is subsequently removed and the remaining solution of D-galactose is subjected to enzymatic isomerisation with an L-arabinose isomerase to obtain D-tagatose. The L-arabinose isomerase preparations used are crude biomass extracts of Lactobacillus pentosus, Bacillus amyloliquefaciens or Arthrobacter spp

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