HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → 1-(4-AMino-2-Methylsulfanyl-pyriMidin-5-yl)-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | [4-Amino-2-(methylsulfanyl)pyrimidin-5-yl]methanol | HCID 220531 | — |
| Product | 1-(4-AMino-2-Methylsulfanyl-pyriMidin-5-yl)-ethanone | HCID 11183013 | 72% |
Reaction Steps
By substituting 1-(4-amino-2-methylsulfanyl-pyrimidin-5-yl)-ethanol (Example 34) for (4-amino-2-methylsulfanyl-pyrimidin-5-yl)-methanol in Example 3 and conducting the reaction at 80° C. in toluene, 3.74 g (72%) of the product as a solid is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053070B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-17c280d8d11447929951c2603eef6d8b |
| Source note | uspto-grants-2006_05 |