Diethyl Ether → HCID 86587672, compound

HRID 1826590Notes

Reaction equation

HRID 1826590 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:17]([NH2:18])=[N:16][C:9]2[N:10]=[C:11](SC)[N:12]=[CH:13][C:8]=2[CH:7]=1)=[O:5])[CH3:2].S(Cl)([Cl:22])(=O)=O.CCOCC>C(Cl)(Cl)Cl.C(O)C>[CH2:1]([O:3][C:4]([C:6]1[C:17]([NH2:18])=[N:16][C:9]2[N:10]=[C:11]([Cl:22])[N:12]=[CH:13][C:8]=2[CH:7]=1)=[O:5])[CH3:2]

Participants

6

Reactant 3

HCID 3283Diethyl EtherHCID 24648Sulfuryl chlorideHCID 69654678HCID 69654678, compound

Product 1

HCID 86587672HCID 86587672, compoundYield 98%

Reagents, catalysts & solvents 2

HCID 702EthanolCatalystHCID 6212ChloroformSolvent

Procedure

To a suspension of the product of Example 128 in 50 mL of chloroform is slowly added sulfuryl chloride, followed by 2 drops of ethanol. The reaction is stirred at room temperature for 16 hours, poured into ether, and the solid collected to give 0.50 g (98%) of the product.

Workup

  1. customthe solid collected

Sources & evidence

ORD record
ord-c4643fe8a8bf4784932067944aac0b55
Source dataset
uspto-grants-2006_05
Patent number
US07053070B2

Reaction notes

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