Methyl 4-[(2-benzyloxyphenyl)hydroxymethyl]benzoate → Methyl 4-(2-hydroxybenzyl)benzoate

Participants

Reaction Steps

To a solution of methyl 4-[(2-benzyloxyphenyl)hydroxymethyl]benzoate (2.6 g) in ethanol (15 mL) was added 10% palladium-carbon powder (0.50 g), and the mixture was stirred under a hydrogen atmosphere at room temperature for 18 hours. An insoluble material was removed by filtration, and the solvent of the filtrate was removed under reduced pressure to give methyl 4-(2-hydroxybenzyl)benzoate (1.7 g).

Provenance & Evidence