3-(2-formyl-4,5,6,7-tetrahydro-1H-indol-3-yl)propionic acid → HCID 69584239, compound

HRID 1826732Notes

Reaction equation

HRID 1826732 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)=[CH:3][CH:2]=1.[CH:17]([C:19]1[NH:20][C:21]2[CH2:22][CH2:23][CH2:24][CH2:25][C:26]=2[C:27]=1[CH2:28][CH2:29][C:30]([OH:32])=[O:31])=O>>[O:16]=[C:10]1[C:9](=[CH:17][C:19]2[NH:20][C:21]3[CH2:22][CH2:23][CH2:24][CH2:25][C:26]=3[C:27]=2[CH2:28][CH2:29][C:30]([OH:32])=[O:31])[C:8]2[C:12](=[CH:13][CH:14]=[CH:15][C:7]=2[C:4]2[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=2)[NH:11]1

Participants

3

Reactant 2

HCID 106090023-(2-formyl-4,5,6,7-tetrahydro-1H-indol-3-yl)propionic acidHCID 121115814-Pyridin-4-yl-1,3-dihydro-indol-2-one

Product 1

HCID 69584239HCID 69584239, compound

Procedure

4-Pyridin-4-yl-1,3-dihydroindol-2-one was condensed with 3-(2-formyl-4,5,6,7-tetrahydro-1H-indol-3-yl)-propionic acid to give the title compound.

Sources & evidence

ORD record
ord-b46c49f662b344b99ca7d7e517653fca
Source dataset
uspto-grants-2006_05
Patent number
US07053086B2

Reaction notes

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