4-Pyridin-4-yl-1,3-dihydro-indol-2-one → 2,4-Dimethyl-5-(2-oxo-4-pyridin-4-yl-1,2-dihydroindol-3-ylidene-methyl)-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide

HRID 1826744Notes

Reaction equation

HRID 1826744 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)=[CH:3][CH:2]=1.[CH2:17]([N:19]([CH2:34][CH3:35])[CH2:20][CH2:21][NH:22][C:23]([C:25]1[C:29]([CH3:30])=[C:28]([CH:31]=O)[NH:27][C:26]=1[CH3:33])=[O:24])[CH3:18]>>[CH2:34]([N:19]([CH2:17][CH3:18])[CH2:20][CH2:21][NH:22][C:23]([C:25]1[C:29]([CH3:30])=[C:28]([CH:31]=[C:9]2[C:8]3[C:12](=[CH:13][CH:14]=[CH:15][C:7]=3[C:4]3[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=3)[NH:11][C:10]2=[O:16])[NH:27][C:26]=1[CH3:33])=[O:24])[CH3:35]

Participants

3

Reactant 2

HCID 121115814-Pyridin-4-yl-1,3-dihydro-indol-2-oneHCID 20761785N-(2-(diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide

Product 1

HCID 725169212,4-Dimethyl-5-(2-oxo-4-pyridin-4-yl-1,2-dihydroindol-3-ylidene-methyl)-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide

Procedure

4-Pyridin-4-yl-1,3-dihydroindol-2-one was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)-amide to give the title compound.

Sources & evidence

ORD record
ord-8e58fe0618c14bbbb901f1b34c9a13f0
Source dataset
uspto-grants-2006_05
Patent number
US07053086B2

Reaction notes

Loading…