HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Oxo-2,4,6,7-tetrahydropyrano[3,4-C]pyrrole-1-carbaldehyde → HCID 49823029, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Oxo-2,4,6,7-tetrahydropyrano[3,4-C]pyrrole-1-carbaldehyde | HCID 9834049 | — |
| Reactant | 4-(Piperidin-4-yl)indolin-2-one | HCID 22135396 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 49823029 | HCID 49823029 | 28% |
Reaction Steps
A mixture of 4-piperidin-4-yl-1,3-dihydroindol-2-one (117 mg, 0.54 mmol), 4-oxo-2,4,6,7-tetrahydropyrano[3,4-c]pyrrole-1-carbaldehyde (89.3 mg, 0.54 mmol) and piperidine (1 drop) in ethanol (3 mL) was stirred at room temperature for 2 days. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give 54.1 mg (28%) of the title compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053086B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-683ecfd20f0f40ea9d22331da33c1e3c |
| Source note | uspto-grants-2006_05 |