Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 3,5-Dimethyl-1H-pyrrole-2-carbaldehyde | HCID 270465 | — |
| Reactant | 4-(Piperidin-4-yl)indolin-2-one | HCID 22135396 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 69584265 | HCID 69584265 | — |
Reaction Steps
A mixture of 4-piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol), 3,5-dimethyl-1H-pyrrole-2-carbaldehyde (29 mg, 0.23 mmol) and pyrrolidine (0.006 mL) in ethanol (0.5 mL) was refluxed for 2 hours at 90° C. The reaction was cooled and the precipitate which formed was collected by vacuum filtration, washed with ethanol and dried to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07053086B2 |
|---|
| Source dataset | uspto-grants-2006_05 |
|---|
| ORD ID | ord-bc35ffb122ee4502a2176050b74101a3 |
|---|
| Source note | uspto-grants-2006_05 |
|---|
